DOG international: Sessions in English

Sharing knowledge and experiences with leading international experts is one of the DOG’s priorities. Our English-language sessions offer the opportunity to share clinical best practices and research perspectives with colleagues from other countries.

The complete English language program as PDF download.

Nairobi 3&4 08:30 - 09:45 28.09.2018
Symposien Fr05
Keratomycosis - Evidence in diagnosis and treatment
Fungal keratitis is a serious and increasingly frequent infection, often associated with contact lens wear. This symposium presents new results on molecular biological as well as clinical diagnostic approaches and treatment from the German keratomycosis registry and a number of international studies.
Gerd Geerling, Klinikdirektor (Düsseldorf)
Berthold Seitz, Direktor der Klinik für Augenheilkunde (Homburg/Saar)
Gerd Geerling, Klinikdirektor (Düsseldorf)
The clinical findings from the German Keratomycosis registry will be presented, which includes data from more than 120 cases so far. The changing risk factors for corneal fungal infections of corneal fungal infections in Germany will be discussed.
Oliver Kurzai (Würzburg)
Based on data from the German National Reference Center for Invasive Fungal Infections (NRZMyk) an overview on the mould species causing fungal keratitis in Germany will be presented. Besides the most common agents from the genus Fusarium, a broad variety of genera and species can be found, which differ in their antifungal susceptibility in vitro. Conventional and molecular tools for diagnosis of fungal keratitis will be discussed.
Matthew Burton (London)
Diagnosing fungal keratitis can be difficult. This talk will review published data on the clinical presentation that can alert the clinician to the possibility of fungal infection. It will also review the use and added value of In Vivo Confocal Microscopy in complementing microbiological investigations.
Wolfgang Behrens-Baumann (Göttingen/Magdeburg)
In this lecture new antimycotics – e.g. isavuconazole – and old drugs with new indications – e.g. terbinafine – will be presented as well as the established antifungals like voriconazole or natamycin. Frequency of drop application, intracorneal, intracameral and intravitreal (IVOM) administration will be discussed. The importance of molecular mass for penetration into the cornea will be emphasized with the consequence of epithelial debridement in corresponding cases.
Berthold Seitz, Direktor der Klinik für Augenheilkunde (Homburg/Saar)
In case of progressive therapy-resistant mycotic keratitis, a penetrating (!) keratoplasty with a large graft diameter (9 to 13 mm, 0.5 mm donor oversize) to ensure sufficient distance to the infiltrate, and multiple interrupted sutures (e.g. 32 !) should be performed within days or weeks. A careful removal of all the infiltrates and hypopyon in the anterior chamber, circular intrastromal injection of voriconacol into the host rim and multiple post-PKP anterior chamber washouts with vancomycin seem to be advisable. As soon as the fungus (especially Fusarium solani) has invaded the anterior chamber through Descemet’s membrane (!), the prognosis tends to be worse despite lentectomy, vitrectomy and repetitive antimycotic anterior chamber washouts every other day. Enucleation should be prevented by early intervention!